SEPTERNA INC - Security Detail

Period	Total Value	Value Change	Total Holders	Holder Change
2024-12-31	$1.00B	-	69	-

Institution	Value	Shares	% of Portfolio
TRV GP VI, LLC	$72.2M	3,152K	61.8%
TRV GP V, LLC	$142.3M	6,215K	48.4%
SAMSARA BIOCAPITAL, LLC	$63.4M	2,768K	8.7%
CATALIO CAPITAL MANAGEMENT, LP	$23.5M	1,024K	5.1%
SIREN, L.L.C.	$50.4M	2,202K	2.2%
RA CAPITAL MANAGEMENT, L.P.	$160.2M	6,995K	2.1%
BVF INC/IL	$56.2M	2,452K	1.9%
SIO CAPITAL MANAGEMENT, LLC	$6.2M	271K	1.8%
DEEP TRACK CAPITAL, LP	$43.8M	1,912K	1.6%
SOLEUS CAPITAL MANAGEMENT, L.P.	$15.5M	675K	1.0%
CASDIN CAPITAL, LLC	$12.7M	553K	0.8%
CORMORANT ASSET MANAGEMENT, LP	$12.8M	560K	0.7%
DRIEHAUS CAPITAL MANAGEMENT LLC	$59.3M	2,589K	0.5%
PERCEPTIVE ADVISORS LLC	$17.2M	750K	0.5%
DEERFIELD MANAGEMENT COMPANY, L.P.	$19.7M	861K	0.4%
AVORO CAPITAL ADVISORS LLC	$25.4M	1,110K	0.4%
LOGOS GLOBAL MANAGEMENT LP	$3.1M	134K	0.4%
WOODLINE PARTNERS LP	$6.9M	300K	0.1%
ARROWMARK COLORADO HOLDINGS LLC	$3.4M	147K	0.1%
LINDBROOK CAPITAL, LLC	$0.5M	21K	0.0%
OCONNOR, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS	$0.3M	12K	0.0%
ADAGE CAPITAL PARTNERS GP, L.L.C.	$6.9M	300K	0.0%
JANUS HENDERSON GROUP PLC	$25.1M	1,096K	0.0%
GOLDMAN SACHS GROUP INC	$38.3M	1,674K	0.0%
VANGUARD GROUP INC	$22.6M	985K	0.0%

Ticker	Exchange	Security	Similarity Score	Common Holders	Total Holders
GHRS	US	GH RESEARCH PLC	0.065	2	31
ABVX	US	ABIVAX SA-ADR	0.043	2	46
CRGX	US	CARGO THERAPEUTICS INC	0.042	4	95
BCAX	US	BICARA THERAPEUTICS INC	0.038	3	80
TARA	US	PROTARA THERAPEUTIC INC	0.034	2	58
RAPP	US	RAPPORT THERAPEUTICS INC	0.030	2	67
TYRA	US	TYRA BIOSCIENCES INC	0.028	3	107
CLYM	US	CLIMB BIO INC	0.027	2	75
GLPG	US	GALAPAGOS NV-SPON ADR	0.027	2	75
GPCR	US	STRUCTURE THERAPEUTICS INC	0.026	4	155
KRRO	US	KORRO BIO INC	0.025	2	81
NMRA	US	NEUMORA THERAPEUTICS INC	0.024	3	124
BCYC	US	BICYCLE THERAPEUTICS PLC-ADR	0.023	2	87
LENZ	US	LENZ THERAPEUTICS INC	0.023	2	87
DNTH	US	DIANTHUS THERAPEUTICS INC	0.022	2	92
ETNB	US	89BIO INC	0.021	3	146
MLYS	US	MINERALYS THERAPEUTICS INC	0.019	2	104
ATXS	US	ASTRIA THERAPEUTICS INC	0.019	2	105
CNTA	US	CENTESSA PHARMACEUTICALS-ADR	0.019	2	106
KURA	US	KURA ONCOLOGY INC	0.018	3	171
VRNA	US	VERONA PHARMA PLC - ADR	0.017	3	175
NAMS	US	NEWAMSTERDAM PHARMA CO NV	0.016	2	125
DYN	US	DYNE THERAPEUTICS INC	0.016	3	189
EWTX	US	EDGEWISE THERAPEUTICS INC	0.015	3	195
ASND	US	ASCENDIS PHARMA A/S - ADR	0.015	3	197