SPDR S&P BIOTECH ETF - Security Detail

Period	Total Value	Value Change	Total Holders	Holder Change
2024-06-30	$9.14B	-	747	-
2024-09-30	$10.13B	+10.8%	755	+1.1%
2024-12-31	$10.47B	+3.3%	564	-25.3%

Institution	Value	Shares	% of Portfolio
SOLEUS CAPITAL MANAGEMENT, L.P.	$270.2M	3,000K	17.0%
ALLOSTERY INVESTMENTS LP	$15.8M	175K	16.5%
Q GLOBAL ADVISORS, LLC	$16.8M	170K	13.3%
IKARIAN CAPITAL, LLC	$67.5M	750K	9.2%
DAFNA CAPITAL MANAGEMENT LLC	$35.8M	397K	9.1%
AFFINITY ASSET ADVISORS, LLC	$67.5M	750K	9.1%
IKARIAN CAPITAL, LLC	$63.0M	700K	8.6%
DIADEMA PARTNERS LP	$18.0M	200K	7.7%
CHIRON CAPITAL MANAGEMENT, LLC	$7.9M	87K	7.4%
NANTAHALA CAPITAL MANAGEMENT, LLC	$112.6M	1,250K	4.8%
PARKWOOD LLC	$41.4M	4K	4.7%
MIRAE ASSET SECURITIES INC.	$135.1M	1,500K	4.1%
BLUECREST CAPITAL MANAGEMENT LTD	$138.1M	1,532K	3.9%
OMNIA FAMILY WEALTH, LLC	$8.7M	87K	3.7%
TED BUCHAN & CO	$7.7M	85K	3.6%
LHM, INC.	$11.2M	123K	3.6%
ARTIA GLOBAL PARTNERS LP	$9.0M	100K	3.2%
INVESTURE, LLC	$50.6M	561K	3.0%
OXFORD ASSET MANAGEMENT LLP	$5.7M	63K	3.0%
LUMBARD & KELLNER, LLC	$6.9M	76K	3.0%
UNITED CAPITAL MANAGEMENT OF KS, INC.	$15.6M	173K	2.8%
BOOTHE INVESTMENT GROUP, INC.	$5.8M	63K	2.5%
ARCADIA WEALTH MANAGEMENT, INC.	$2.9M	32K	2.5%
IRON TRIANGLE PARTNERS LP	$22.5M	250K	2.5%
QUANTESSENCE CAPITAL LLC	$5.8M	64K	2.4%

Ticker	Exchange	Security	Similarity Score	Common Holders	Total Holders
EIDO	US	ISHARES MSCI INDONESIA ETF	0.027	2	74
ATXS	US	ASTRIA THERAPEUTICS INC	0.019	2	105
MAGS	US	ROUNDHILL MAGNIFICENT SEVEN	0.017	2	120
ASND	US	ASCENDIS PHARMA A/S - ADR	0.015	3	197
KRNT	US	KORNIT DIGITAL LTD	0.014	2	147
XME	US	SPDR S&P METALS & MINING ETF	0.013	3	227
DAWN	US	DAY ONE BIOPHARMACEUTICALS I	0.013	2	153
KURA	US	KURA ONCOLOGY INC	0.012	2	171
EWTX	US	EDGEWISE THERAPEUTICS INC	0.010	2	195
MCHI	US	ISHARES MSCI CHINA ETF	0.009	2	213
PYLD	US	PIMCO MULTISECTOR BOND ACTV	0.009	2	235
GDXJ	US	VANECK JUNIOR GOLD MINERS	0.008	2	262
PRGO	US	PERRIGO CO PLC	0.007	2	303
TEVA	US	TEVA PHARMACEUTICAL-SP ADR	0.006	3	487
JMST	US	JPM ULTRA-SHORT MUNI INCOME	0.006	2	328
RSP	US	INVESCO S&P 500 EQUAL WEIGHT	0.006	8	1336
NICE	US	NICE LTD - SPON ADR	0.006	2	341
SDVY	US	FIRST TRUST SMID CAP RISING	0.006	2	361
BABA	US	ALIBABA GROUP HOLDING-SP ADR	0.005	5	942
XLU	US	UTILITIES SELECT SECTOR SPDR	0.005	5	963
PBR	US	PETROLEO BRASILEIRO-SPON ADR	0.005	2	395
AAPL	US	APPLE INC	0.005	20	3956
FDN	US	FIRST TRUST DJ INTERNET IND	0.005	2	427
XLK	US	TECHNOLOGY SELECT SECT SPDR	0.005	7	1506
IBB	US	ISHARES BIOTECHNOLOGY ETF	0.005	3	655