PRAXIS PRECISION MEDICINES I - Security Detail

Security Name:	PRAXIS PRECISION MEDICINES I
Ticker:	PRAX
Security Type:	EQU
Exchange:	US
CUSIP:	74006W207

Period	Total Value	Value Change	Total Holders	Holder Change
2024-06-30	$0.76B	-	114	-
2024-09-30	$1.09B	+43.2%	134	+17.5%
2024-12-31	$1.62B	+48.9%	156	+16.4%

Institution	Value	Shares	% of Portfolio
VELAN CAPITAL INVESTMENT MANAGEMENT LP	$23.1M	300K	19.9%
72 INVESTMENT HOLDINGS, LLC	$5.1M	65K	10.3%
CORMORANT ASSET MANAGEMENT, LP	$130.3M	1,693K	7.2%
ACUTA CAPITAL PARTNERS, LLC	$5.2M	67K	5.2%
VR ADVISER, LLC	$76.2M	989K	5.2%
KINGDON CAPITAL MANAGEMENT, L.L.C.	$23.3M	303K	3.3%
5AM VENTURE MANAGEMENT, LLC	$13.1M	170K	3.1%
ALLY BRIDGE GROUP LLC	$3.5M	44K	3.0%
PERCEPTIVE ADVISORS LLC	$102.3M	1,329K	2.8%
STEMPOINT CAPITAL LP	$10.3M	134K	2.6%
SPHERA FUNDS MANAGEMENT LTD.	$7.0M	91K	1.3%
SILVERARC CAPITAL MANAGEMENT, LLC	$5.6M	72K	1.2%
SOLEUS CAPITAL MANAGEMENT, L.P.	$18.7M	243K	1.2%
SPHERA FUNDS MANAGEMENT LTD.	$6.4M	83K	1.2%
PERCEPTIVE ADVISORS LLC	$38.5M	500K	1.1%
RA CAPITAL MANAGEMENT, L.P.	$58.6M	761K	0.8%
FIRST TURN MANAGEMENT, LLC	$3.5M	45K	0.6%
TRI LOCUM PARTNERS LP	$2.9M	37K	0.6%
PFM HEALTH SCIENCES, LP	$9.2M	119K	0.6%
HIGHVISTA STRATEGIES LLC	$0.8M	10K	0.3%
BAKER BROS. ADVISORS LP	$25.5M	331K	0.3%
HUSSMAN STRATEGIC ADVISORS, INC.	$0.8M	10K	0.2%
SIMPLIFY ASSET MANAGEMENT INC.	$3.3M	43K	0.2%
OCONNOR, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS	$2.0M	26K	0.2%
VERITION FUND MANAGEMENT LLC	$35.7M	464K	0.1%

Ticker	Exchange	Security	Similarity Score	Common Holders	Total Holders
HLXB	US	HELIX ACQUISITION CORP II	0.125	4	32
PHVS	US	PHARVARIS NV	0.091	5	55
ENGN	US	ENGENE HOLDINGS INC	0.086	3	35
JSPR	US	JASPER THERAPEUTICS INC	0.072	6	83
DRUG	US	BRIGHT MINDS BIOSCIENCES INC	0.067	2	30
IKT	US	INHIBIKASE THERAPEUTICS INC	0.065	2	31
CNTA	US	CENTESSA PHARMACEUTICALS-ADR	0.057	6	106
CDTX	US	CIDARA THERAPEUTICS INC	0.049	2	41
ELVN	US	ENLIVEN THERAPEUTICS INC	0.047	5	107
ABVX	US	ABIVAX SA-ADR	0.043	2	46
ELDN	US	ELEDON PHARMACEUTICALS INC	0.041	3	73
MRUS	US	MERUS NV	0.038	7	182
AADI	US	AADI BIOSCIENCE INC	0.038	2	52
ARTV	US	ARTIVA BIOTHERAPEUTICS INC	0.037	2	54
TARA	US	PROTARA THERAPEUTIC INC	0.034	2	58
ALMS	US	ALUMIS INC	0.034	2	58
CTNM	US	CONTINEUM THERAPEUTICS INC-A	0.034	2	59
DNTH	US	DIANTHUS THERAPEUTICS INC	0.033	3	92
TRML	US	TOURMALINE BIO INC	0.031	3	98
EYPT	US	EYEPOINT PHARMACEUTICALS INC	0.030	4	133
TECX	US	TECTONIC THERAPEUTIC INC	0.029	2	68
TRVI	US	TREVI THERAPEUTICS INC	0.029	3	104
RZLT	US	REZOLUTE INC	0.028	2	71
SKYE	US	SKYE BIOSCIENCE INC	0.027	2	73
EWTX	US	EDGEWISE THERAPEUTICS INC	0.026	5	195